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Botox Units Required for Hyperhidrosis (Excessive Sweating) by Body Area

SKINFUDGE Clinics

Body Area Total Units Needed Units Per Side Injection Sites Duration Pain Level FDA Approval
Underarms (Axillary) 50–100 units 25–50 units per side 10–15 per armpit 4–6 months 🟒 Low βœ… Yes
Palms (Hands) 100–200 units 50–100 units per hand 20–30 per palm 4–6 months πŸ”΄ High ❌ No (Off-label)
Soles (Feet) 100–200 units 50–100 units per foot 20–30 per sole 4–6 months πŸ”΄ High ❌ No (Off-label)
Scalp (Craniofacial) 75–150 units N/A (varied areas) Scattered along hairline & scalp 4–6 months 🟑 Medium ❌ No (Off-label)
Forehead & Face 40–60 units N/A (varied areas) 10–20 points 3–5 months 🟑 Medium ❌ No (Off-label)
Groin & Under-Breast 50–100 units N/A (varied areas) Along skin folds 4–6 months 🟒 Low-Medium ❌ No (Off-label)

Notes:

βœ” Results appear in 3–7 days, peak at 2 weeks.
βœ” Repeat treatments are needed every 4–6 months.
βœ” Pain levels varyβ€”palms, soles, and scalp require numbing or anesthesia.
βœ” Only underarm hyperhidrosis is FDA-approved; all other areas are treated off-label.

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About the Author

Dr. Burhan Hussein, MBBS, MD (USA), MSc Dermatology (UK), MACP (USA), is a highly qualified physician with extensive international training in internal medicine, dermatology, and aesthetic medicine. He is a member of the American Medical Association, the American College of Physicians, the Royal College of Physicians, and the American Academy of Aesthetic Medicine. With years of clinical experience and a commitment to evidence-based care, Dr. Hussein provides trustworthy, expert-backed insights to help readers make informed decisions about their health and skin.