Sardenya Nucleo with Lidocaine

Skin Rejuvenation Booster with Polynucleotides & Comfort Agent

Origin & Manufacturing

• Developed by RFBio Co., Ltd. in South Korea.

• Manufactured under controlled conditions and high purity standards.

• Includes 0.3% lidocaine to reduce injection discomfort.

Composition / Ingredients

While full proprietary details are often reserved, the key components are:

• Polynucleotides (PN / Nucleic acid fragments) — intended to stimulate tissue regeneration, repair, and collagen/elastic fiber synthesis.

• Hyaluronic Acid (likely a non-crosslinked form) — provides hydration and volume support.

• Lidocaine 0.3% — local anesthetic to enhance patient comfort during the procedure.

Other supporting excipients (buffer salts, sterile water, pH adjusters, etc.) are expected but not publicly disclosed.

Indications / Intended Use

Sardenya Nucleo is intended for aesthetic skin revitalization and rejuvenation, particularly for:

• Improving skin texture, tone, and smoothness

• Stimulating skin repair and regeneration

• Reducing the appearance of fine lines and superficial wrinkles

• Enhancing hydration and elasticity

• Brightening dull or aged skin

This type of product is typically used in mesotherapy, injection points across the face, neck, or hands, and in areas needing revitalization rather than high-volume structural effect.

Effects / Benefits

• Regenerative stimulation — the PN encourages fibroblast activation, collagen & elastin production, and repair of micro-damage.

• Hydration & plumping — the HA component attracts moisture, improving skin turgor and suppleness.

• Smoother texture & glow — over time, fine lines soften, skin tone becomes more even, and overall radiance improves.

• Comfort during the procedure — inclusion of lidocaine reduces pain and improves patient experience.

• Safe absorption & integration — designed to be biocompatible and gradually metabolized by the body.