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Terizole (Itraconazole) 100mg x 4 Capsules

Terizole (Itraconazole) 100mg x 4 Capsules

Rs.485.00 PKR
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Terizole (Itraconazole) 100mg x 4 Capsules

Terizole (Itraconazole) 100mg x 4 Capsules

By Wisdom

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Rs.485.00 PKR

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traconazole 100mg capsules exert their antifungal activity primarily through the inhibition of ergosterol synthesis. Ergosterol is a crucial component of fungal cell membranes. The drug binds to the cytochrome P450 enzyme lanosterol 14α-demethylase, which is responsible for converting lanosterol to ergosterol. By inhibiting this enzyme, itraconazole disrupts the fungal cell membrane structure and function, leading to impaired membrane integrity and ultimately, fungal cell death. This selective inhibition of fungal sterol synthesis is the key mechanism through which itraconazole exhibits its potent antifungal effects, without significantly affecting mammalian cells that do not produce ergosterol.

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